Expression of procaspase 3 in HD.

(A) In this patient with HD, all H/RS cells expressed procaspase 3 at levels similar to those for the reactive infiltrating lymphocytes that served as an internal positive control. (B) Absence of procaspase 3 in the H/RS cells and strongly positive reactive lymphocytes. Expression of active caspase 3 and PARP-1/p89 in the neoplastic cells was not observed in this patient (Figure 3B,D). Original magnification × 630.