Relationship between number of transplanted FL, FBM, and FB hematopoietic cells and chimerism in NOD/SCID recipients.

Mice were transplanted with G₀CD34⁺, G₁CD34⁺, or S/G₂+MCD34⁺cells from FL or FBM or with G₀CD34⁺Lin⁻ or G₁CD34⁺Lin⁻ cells from FB. Chimerism was defined as the percentage of human CD45⁺cells detected in BM (blue diamonds), spleen (red squares), or peripheral blood (yellow triangles) of recipient NOD/SCID mice 8 weeks after transplantation. Each point represents the level of chimerism in one tissue of one mouse. Note that the number of cells used in transplantation of fetal blood cells is different than that used for fetal liver and bone marrow, as is shown by the scale of the x-axis in the respective plots.