Vaccine regimens including FL as a vaccine adjuvant were ineffective in generating detectable HER-2/neu–specific T-cell proliferative responses.

Patients who received FL alone are shown as ○; patients who received FL and GM-CSF are shown as □. (A) Responses against peptide p776. (B) Responses against p927. (C) Responses against p1166. (D) Responses against the HER-2/neu ICD protein. Data are expressed as a stimulation index. Each symbol represents data on an individual patient. Bold bars indicate the mean response for that group.