Fig. 1.
![Fig. 1. CTCL cells proliferate only in the presence of APCs. / CTCL cells were obtained from 1- (▪) and 3-month (▨) cultures of 2 representative patients and were freed of APCs by CD2–magnetic bead enrichment. The purified CTCL cells were readded after overnight culture to γ-irradiated autologous APCs that had been CTCL cell bead-depleted. After 3 additional days of culture, only CTCL cells cocultivated with APCs proliferated, as shown by uptake of [3H]-thymidine. The results presented are the means of 5 replicate samples ± SD.](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/99/8/10.1182_blood.v99.8.2929/4/h80822428001.jpeg?Expires=1722403960&Signature=AGGMemFQ-mR~cBjBO0zx7W9iYp5-xpYnnL4-awMvTvZCkTaaqgQR7yDVzrSi9KqPtx5nBxNJfOmGpCBp-yZv6l29dOALY9HgB2O-2bMF6hBEsgLOv7TgIeyIvvW3FU1OoGrf2F6GgN7XzJHojRI9VF6JS2Jvy-NXP5MDsEaA9636qv~JCP1J6bZNWDBkJ32fDntlaIYRFIY5OjH6HhkFma~q4DroNWgtNuW-lhMtnXqSobd0Kl32ow5XAkppMcpU3hFadpfqmeFSxKoV67e~KkAerN2sORLz~KsI9057gDs7NsCHw-~2ma1O7aKSnB14hm0D~KBhSRkT-6RRQVQS3Q__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
CTCL cells proliferate only in the presence of APCs.
CTCL cells were obtained from 1- (▪) and 3-month (▨) cultures of 2 representative patients and were freed of APCs by CD2–magnetic bead enrichment. The purified CTCL cells were readded after overnight culture to γ-irradiated autologous APCs that had been CTCL cell bead-depleted. After 3 additional days of culture, only CTCL cells cocultivated with APCs proliferated, as shown by uptake of [3H]-thymidine. The results presented are the means of 5 replicate samples ± SD.
