Chymotrypsin eliminates the invasion of P yoelii into murine normocytes.

RBCs from normal BALB/c mice were treated with chymotrypsin (1 mg/mL), trypsin (1 mg/mL), neuraminidase (50 U/mL), or buffer only, and the invasion rate was measured using in vivo invasion assay. Data are reported as the mean ± SD of thiazole orange–positive transfused cells. Significant difference (P < .05) is represented by an asterisk. Invasion was eliminated in chymotrypsin-treated RBCs.