The difference in parasitemia between

P yoelii–infected DKO and WT mice decreases when reticulocytes enter the circulation. Data shown are derived from one representative infection experiment and are presented as the mean of 6 infected mice in each group. (A) There is a dramatic increase in the percentage of circulating reticulocytes beginning at day 10 after infection. (B) This corresponds to a drop in the fold difference in parasitemia from 4.8 (day 7) to 1.6 (day 10).