Fig. 10.
Fig. 10. PMA-induced differentiation is altered in THP-1 cells expressing wild-type PAI-2. / THP-1 cells stably transfected with pCI-neo (A,D), expressing wild-type PAI-2 (THP-1/PAI-2wt; [B,E]), or mutant PAI-2 (THP-1/PAI-2Ala380 [C,F]) were cultured in the absence (A-C) or presence (D-F) of 25 nM PMA. Phase contrast photomicrographs (magnification × 400) were taken after 5 days of treatment.

PMA-induced differentiation is altered in THP-1 cells expressing wild-type PAI-2.

THP-1 cells stably transfected with pCI-neo (A,D), expressing wild-type PAI-2 (THP-1/PAI-2wt; [B,E]), or mutant PAI-2 (THP-1/PAI-2Ala380 [C,F]) were cultured in the absence (A-C) or presence (D-F) of 25 nM PMA. Phase contrast photomicrographs (magnification × 400) were taken after 5 days of treatment.

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