Fig. 1.
Fig. 1. Eμ-A1 transgenic mice. / (A) Eμ-A1 transgene construct, containing full-length A1-acDNA, Eμ enhancer, and H-2Kb promoter. (B) A1 mRNA expression in transgenic mice and wild-type littermates. Ribonuclease protection assays for A1-a and GAPDH control are shown for the indicated tissues for line 8 mice. (C) Overexpression ofA1-a mRNA in 3 Eμ-A1 transgenic mouse lines. Figures represent -fold increases in A1-a mRNA in the indicated tissues over those of wild-type littermates. Results are the mean from 2 animals of each genotype and are normalized to the GAPDH signal.

Eμ-A1 transgenic mice.

(A) Eμ-A1 transgene construct, containing full-length A1-acDNA, Eμ enhancer, and H-2Kb promoter. (B) A1 mRNA expression in transgenic mice and wild-type littermates. Ribonuclease protection assays for A1-a and GAPDH control are shown for the indicated tissues for line 8 mice. (C) Overexpression ofA1-a mRNA in 3 Eμ-A1 transgenic mouse lines. Figures represent -fold increases in A1-a mRNA in the indicated tissues over those of wild-type littermates. Results are the mean from 2 animals of each genotype and are normalized to the GAPDH signal.

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