Activation of Erk-1/2 in response to CSF-1 is diminished by protease inhibitor LLnL.

BMMs from ICSBP^+/+ mice were incubated in the presence or absence of 25 μM LLnL and deprived of CSF-1 simultaneously for 12 hours. The cells were then stimulated with 100 ng/mL CSF-1 for the times indicated.