Proviral integration and clonality of tumors.

(A) Proviral integration and (B) T-cell receptor (TCR) rearrangement. Genomic DNA (5 μg) from each indicated mouse tissue was digested with EcoRI and probed with either an IRES probe to detect proviral integration or TCR Jβ1 probe to detect TCR rearrangement status as previously described.17,35 The λHindIII molecular weight marker is shown on the left.