Fig. 6.
Fig. 6. The pattern of IRTA family mRNA expression in cell lines highlights a correlation of IRTA-2 deregulation with chromosome 1q21 abnormalities. / Northern blot analysis of IRTA2, IRTA3, IRTA4, and IRTA5 using 2 overlapping panels of RNA representative of the major hematopoietic lineages and containing BL cell lines of known 1q21 karyotype, 2 μg polyA RNA per lane; 5′ end probes were used for IRTA2 and IRTA4, and 3′ end probes were used for IRTA3 and IRTA5, as shown in Figure 5. Epstein-Barr virus (EBV) status is indicated on the bottom of the figure. GADPH indicates glyceraldehyde phosphate dehydrogenase.

The pattern of IRTA family mRNA expression in cell lines highlights a correlation of IRTA-2 deregulation with chromosome 1q21 abnormalities.

Northern blot analysis of IRTA2, IRTA3, IRTA4, and IRTA5 using 2 overlapping panels of RNA representative of the major hematopoietic lineages and containing BL cell lines of known 1q21 karyotype, 2 μg polyA RNA per lane; 5′ end probes were used for IRTA2 and IRTA4, and 3′ end probes were used for IRTA3 and IRTA5, as shown in Figure 5. Epstein-Barr virus (EBV) status is indicated on the bottom of the figure. GADPH indicates glyceraldehyde phosphate dehydrogenase.

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