Fig. 3.
Fig. 3. Systemic NHL 18 months after MCD diagnosis in patient 7. / Initial lymph node biopsy shows the typical Castleman lesion (A) and the positive staining with the KSHV/HHV8 LNA-1 specific monoclonal antibody (B). Postmortem spleen analysis reveals diffuse infiltration with large/anaplastic cells (C), with positive staining with the KSHV/HHV8 LNA-1 antibody (D), an illegitimate expression of the T-cell CD3 marker (E), and the expression of the CD30 marker (F). Original magnification ×200 in panels A, B, D-F; ×400 in C.

Systemic NHL 18 months after MCD diagnosis in patient 7.

Initial lymph node biopsy shows the typical Castleman lesion (A) and the positive staining with the KSHV/HHV8 LNA-1 specific monoclonal antibody (B). Postmortem spleen analysis reveals diffuse infiltration with large/anaplastic cells (C), with positive staining with the KSHV/HHV8 LNA-1 antibody (D), an illegitimate expression of the T-cell CD3 marker (E), and the expression of the CD30 marker (F). Original magnification ×200 in panels A, B, D-F; ×400 in C.

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