T-cell phenotype analysis in patient 2.

Results obtained from PBMCs collected at +15 weeks from infusion are compared with phenotype analysis performed on the transferred CTL line and on the patient's preinfusion PBMCs. (A,D,G) These panels refer to CD3⁺ cells, (B,E,H) to CD8⁺ subset, and (C,F,I) to T-cell receptor γδ⁺ population. An impressive peripheral expansion of CD8⁺ and T-cell receptor γδ⁺ T cells is observed in the patient after CTL infusion. Data are expressed as the percentage of positive cells.