Comparative PBL transduction efficiency of OKT3-displaying lentiviral vectors versus MLV vectors.

Nonactivated PBLs were incubated with OKT3SU- or OKT3SUx-displaying VSV-G–pseudotyped vector particles derived from HIV-1 or from MLV, as indicated. The number of GFP⁺ cells was determined 6 days after infection by FACS analysis. Results of transduction in PBLs from different donors are given. The PBL sets correspond to those of Figure5. The MOIs are provided for each experiment.