STI571 modulates the activation of NF-κB in UT-7/9 cells.

Confocal microscopy analyses of nuclear localization of NF-κB p65 subunit (green) in UT-7/9 and UT-7 cells in basal condition and treated for 48 hours by STI571. Yellow staining indicates nuclear localization of NF-κB p65 subunit. As control UT-7/9 cells were treated for 16 hours by BAY 11-7082 (a specific inhibitor of NF-κB) before staining. CTRL correspond to nuclear (red) staining by propidium iodide (2 μg/mL) of UT-7/9 cells.