Fig. 1.
Trichrome-stained sections of necropsied liver.
The patient died of multiorgan failure 37 days after receiving the first of 2 doses of Mylotarg (6 mg/m2). Standard bar equals 100 μm. (upper panel) Extensive sinusoidal fibrosis adjacent to a nonoccluded sublobular venule. (lower panel) Zone 3 region containing atrophic hepatocyte cords surrounded by markedly widened sinusoids filled with dense collagen. An adjacent central venule shows eccentric perivenular fibrosis.
