Fig. 8.
![Fig. 8. Transduced cells are rescued to proliferate by stimulation with autologous EBV-LCLs. / 14.G2a-ζ–transduced (A) and nontransduced (B) EBV-specific CTLs were stimulated with irradiated autologous (Auto) or mismatched allogeneic (Allo) LCLs, or with GD2+ (LAN-1) or GD2− (A-204) tumor cells at a 1:4 stimulator-to-responder ratio. After 7 to 14 days, CTLs were stimulated with autologous LCLs (Auto/Auto, LAN-1/Auto, JF/Auto, A-204/Auto, Allo/Auto) or stimulated as before (LAN-1/LAN-1, JF/JF, A-204/A-204, Allo/Allo). Proliferative responses were then assessed by measurement of [3H]-thymidine uptake. Shown is a representative experiment of 2.](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/99/6/10.1182_blood.v99.6.2009/6/h80622263008.jpeg?Expires=1724275909&Signature=Go5-8rD0ut4kh8eUNgwO25epfKbu5zUnkZhyc130WBCpaa7PEjnje50iddqR~3kpsYVnKpTbfIVJPTILaJA7jl5tEE2zG5lsnKozwsrP8BcgXPXs2X9vFFg6v2vR7gKUtZMr6LX0L~JLIEBhKhWUi9x5F2d529o1BDFNK3VkPs~vcXjnKifUyBRFaZESF3hTiCNgMsb0--ovhFQf3qNjnUBsbj4TB7t-OceMieS2yTJs-a8H9ZW0j0EA1Y0kpOFGb~Il5t4FFHk1M7I6aBra08sxxbOpgqho7fU2LqkP-63NtWIcekDvAgZUwPOkCY7EZEQsBuVKt83iAT5UGFbvhg__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Transduced cells are rescued to proliferate by stimulation with autologous EBV-LCLs.
14.G2a-ζ–transduced (A) and nontransduced (B) EBV-specific CTLs were stimulated with irradiated autologous (Auto) or mismatched allogeneic (Allo) LCLs, or with G (LAN-1) or G (A-204) tumor cells at a 1:4 stimulator-to-responder ratio. After 7 to 14 days, CTLs were stimulated with autologous LCLs (Auto/Auto, LAN-1/Auto, JF/Auto, A-204/Auto, Allo/Auto) or stimulated as before (LAN-1/LAN-1, JF/JF, A-204/A-204, Allo/Allo). Proliferative responses were then assessed by measurement of [3H]-thymidine uptake. Shown is a representative experiment of 2.
