American Society of Hematology

Fig. 6.

Cold target inhibition assay.

14.G2a-ζ–transduced EBV-specific CTLs were preincubated with unlabeled autologous LCL (Auto-LCL), HLA-mismatched allogeneic LCL (Allo LCL), G $_{D 2}^{+}$ (LAN-1), or G $_{D 2}^{-}$ (A-204) tumor cells at various cold-to-hot target ratios. Cytotoxic activity was then determined against ⁵¹Cr-labeled autologous LCL (A) and G $_{D 2}^{+}$ LAN-1 tumor cells (B) at an effector-to-target ratio of 40:1.

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