Fig. 3.
Fig. 3. IFN-γ and GM-CSF release by CTLs in response to coincubation with tumor target cells. / Nontransduced (NT) CTLs or CTLs transduced with SFG/14.G2a-ζ were cocultured with tumor cells at a 3:1 target-to-effector ratio for 24 hours. LAN-1 is a GD2+ neuroblastoma cell line and A-204 is a GD2− rhabdomyosarcoma cell line. Numbers above columns indicate the amount of cytokine secretion in response to autologous LCL targets for each population. Data shown are representative of independent experiments performed with CTL lines from 3 donors.

IFN-γ and GM-CSF release by CTLs in response to coincubation with tumor target cells.

Nontransduced (NT) CTLs or CTLs transduced with SFG/14.G2a-ζ were cocultured with tumor cells at a 3:1 target-to-effector ratio for 24 hours. LAN-1 is a GD2+ neuroblastoma cell line and A-204 is a GD2− rhabdomyosarcoma cell line. Numbers above columns indicate the amount of cytokine secretion in response to autologous LCL targets for each population. Data shown are representative of independent experiments performed with CTL lines from 3 donors.

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