Fig. 2.
C1498/B7-2, but not C1498 or C1498/B7-1, induced effective tumor rejection in vivo.
Individual C57BL/6 mice were injected subcutaneously with 1 × 106 live C1498 (n = 16), C1498/B7-1 (n = 13), or C1498/B7-2 (n = 13) tumor cells into the suprascapular region. Survival curves represent the combined results of 4 separate experiments in which all groups were included. Mice that did not die with tumor were killed when the tumor mass was larger than 200 mm2. The lone death on day 50 in the C1498/B7-2 group was not caused by tumor growth. P values represent statistical significance with respect to the C1498-injected group (log-rank test).
