Effect of AT, DEGR-F.Xa, Trp⁴⁹-modified AT, anti-rat TNF-α Ab, AT pretreated with indomethacin (IM), or iloprost on increases in the lung level of iNOS activity 180 minutes after ET administration in rats.

Lung activity of iNOS was determined 180 minutes after ET administration. Concentration of AT, DEGR-F.Xa, Trp⁴⁹-modified AT, anti-rat TNF-α Ab, IM, or iloprost was as in Figures 2A and 12. Control animals were administered saline alone. Data are expressed as means ± SD of 4 animals. *P < .01 versus control. †P < .01 versus ET plus saline.