Fig. 3.
Effect of AT, DEGR-F.Xa, Trp49-modified AT, anti-rat TNF-α Ab, AT pretreated with indomethacin (IM), or iloprost on increases in plasma levels of NO2−/NO3− 180 minutes after ET administration in rats.
Plasma levels of NO2−/NO3− were determined 180 minutes after ET administration. Concentration of AT, DEGR-F.Xa, Trp49-modified AT, anti-rat TNF-α Ab, IM, or iloprost was as in Figures 2A and 12. Control animals were administered saline alone. Data are expressed as means ± SD of 4 animals. *P < .01 versus control. †P < .05 versus ET plus saline. ††P < .01 versus ET plus saline.