BAEC migration in the presence of PDGF-AA.

BAEC migration in response to PDGF-BB or bFGF, alone or in combination (10 ng/mL), was examined in the absence and in the presence of PDGF-AA (10 ng/mL). PDGF-AA showed no chemotactic effect on BAEC, but it inhibited bFGF-induced migration, and the magnitude of this effect was comparable to that of an equal concentration of PDGF-BB. Data are expressed as average ± SD of 3 experiments carried out in duplicate.