Fig. 6.
Morphological changes in K562 cell lines induced to overexpress Gab2.
K562-derived cell lines pSTAR-2, Gab2WT-3, Gab2WT-6, Gab2WT-7, or Gab2Tyr604Phe-5 were plated (5 × 104 cells/mL) in 6-well plates and treated with or without dox for 6 days. Cell were digitally photographed at × 400 magnification with a Nikon TE300 microscope equipped with a CCD camera (Diagnostic Instruments, Sterling Heights, MI). Arrowhead indicates cells that are flattened and adherent to the plates; arrow, enlarged cells.
