Production of MIP-1α and MCP-1 on EBV infection and LPS or PHA costimulation.

PBMC cultures were incubated with EBV (strain B95-8, diluted 1:5) for 48 hours. LPS (10 ng/mL) or PHA (1 μg/mL), respectively, were also used as stimulants, either alone or in combination with EBV. MIP-1α (A) and MCP-1 (B) were quantified in culture supernatants by means of ELISA. Shown are mean ± SD of 8 individuals. P values refer to the figure bars combined by the dotted ends of the given lines.