Fig. 7.
Fig. 7. Adhesive interactions between sickle RBCs and endothelium or plasma proteins. / PS indicates phosphatidylserine; GP1b, glycoprotein 1b; α4β1, integrin receptor VLA-4; VCAM-1, vascular cell adhesion molecule-1; αVβ3, integrin vitronectin receptor; B-CAM/LU, basal cell adhesion molecule/Lutheran protein; HSPG, heparan sulfate proteoglycan; SO4 glycolipid, sulfated glycolipid; TSP, thrombospondin; FN, fibronectin; VWF, von Willebrand factor; LM, laminin; and SE matrix, subendothelial matrix. CD47 is also known as the integrin-associated protein or IAP.

Adhesive interactions between sickle RBCs and endothelium or plasma proteins.

PS indicates phosphatidylserine; GP1b, glycoprotein 1b; α4β1, integrin receptor VLA-4; VCAM-1, vascular cell adhesion molecule-1; αVβ3, integrin vitronectin receptor; B-CAM/LU, basal cell adhesion molecule/Lutheran protein; HSPG, heparan sulfate proteoglycan; SO4 glycolipid, sulfated glycolipid; TSP, thrombospondin; FN, fibronectin; VWF, von Willebrand factor; LM, laminin; and SE matrix, subendothelial matrix. CD47 is also known as the integrin-associated protein or IAP.

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