Regression of tumors after booster vaccination with Id-KLH + chemical adjuvant.

Patient D12 was given Id-pulsed DC vaccination during first remission after chemotherapy but relapsed 15 months later. Subsequent to the development of widespread disease 18 months later, she was given injections of Id-KLH protein plus a chemical adjuvant. (A) CT images of the pelvis show that bulky left-sided pelvic lymph nodes have completely regressed 4 months after booster vaccinations. (B) Regression of axillary (top panels) and inguinal (bottom panels) lymph nodes after booster vaccinations. Arrows indicate sites of disease before vaccination.