Deoxygenation-stimulated K⁺ efflux is reduced in red cells from S+S-Antilles mice that have been supplemented with 5% arginine.

K⁺ efflux was measured in RBCs that were incubated in media that were either exposed to room air (Oxy) or bubbled with nitrogen to deoxygenate them (Deoxy), from mice that were on regular chow (Chow) and after they were supplemented with the 5% arginine diet (+Arg) for 10 weeks. Each point represents the average of one experiment performed in triplicate on one mouse as described in “Materials and methods.” The lines connect the same mouse. The Delta bar graphs represent the average of the deoxy-oxy flux in RBCs from mice on normal chow or arginine-supplemented chow.