Fitting of FVIII molecule arrays within the 3D map of the 2D crystal.

Four membrane-bound FVIII molecules were fitted within the calculated 3D electron density of the FVIII 2D crystal. Cα chains are shown in worm presentation: A1, red; A2, yellow; A3, green; C1, magenta; and C2, cyan. Panel A shows the top view, along the z-axis. Panel B shows the side-on view along the y-axis. Panel C shows the side-on view along the x-axis. The membrane surface is denoted by a black dashed line marked M.