BCL10 mutations in MALT-type lymphomas.

(A-C) Direct sequencing results from case 25. (A) Normal DNA derived from whole tissue sections. (B) Normal DNA derived from a small tumor cell cluster obtained by microdissection. (C) Substitution at position 620: T > C in DNA derived from large tumor cell cluster. Residual peak of T indicates the presence of normal alleles. (D-F) Direct sequencing results from case 14. (D) Substitution at position 280: T > G in DNA derived from whole tissue sections. Residual peak of T indicates the presence of normal alleles. (E) Normal DNA in normal cells. (F) Normal DNA in a cell cluster microdissected from the tumor.