Cytolytic activity of NK cells generated in vivo.

CD3⁻NK1.1⁺ NK cells (circles) and CD3⁺NK1.1⁻ T cells (triangles) were purified from splenocytes of mice reconstituted with population e. (A) Freshly sorted cells were tested for cytolytic activity versus YAC-1 thymoma targets. (B) Sorted NK cells (circles) and T cells (triangles) from mice reconstituted with population e (empty symbols) and control B6 mice (filled symbols) were cultured in vitro for 7 days in IL-2 and thereafter tested for cytolytic activity versus sensitive YAC-1 and resistant P815 target cells.