Endogenous IL-10 is required for SDF-1–induced chemotaxis.

Peritoneal cells were labeled with CD19, CD5, and Mac-1 mAbs and tested in Transwell experiments for SDF-1–induced chemotaxis in the presence of an anti–IL-10R or a control Ab. Results (mean ± SEM from 4 experiments) are the numbers of cells migrating to the lower chamber. *P < .05 compared with cells migrating in the presence of SDF-1 and the control Ab.