IL-10 potentiates the chemotactic activity of SDF-1 on peritoneal B lymphocytes.

Peritoneal cells were labeled with CD19, CD5, and Mac-1 mAbs and added to the upper chamber of a Transwell system. The effect of SDF-1 and/or IL-10 on cell migration was evaluated. Cells in the lower chamber at the end of the assay were characterized and counted by flow cytometry. Results (mean ± SEM) are from 9 experiments. *P < .05 and **P < .005 versus cultures in the presence of SDF-1 alone.