Lymphocyte subsets and proliferation to mitogens before transplantation and after transplantation in SCID infants given stem cell transplants in the neonatal period.

(A-B) The mean (± SEM) numbers of T, B, and NK cells at birth (A) and at the latest posttransplantation evaluation (B) for surviving patients according to genotype. ▪, CD3+ T cells; ■, CD20+ B cells; ░, CD16+ NK cells. Normal range represents the 95% confidence interval for healthy infants at birth (A) or for healthy children at 6 years of age (B). (C) The mean (± SEM) counts per minute of^3Hthymidine incorporation by proliferating PBMCs stimulated with PHA (▪), concanavalin A (■), and pokeweed (░) mitogens before transplantation and at the most recent evaluation compared with healthy controls.