Fig. 1.
![Fig. 1. ATP-triggered lymphocyte [Ca++] increase. / ATP triggers a higher [Ca++]iincrease in lymphocytes from evolutive (A) compared with indolent (B) B-CLL. Lymphocytes were isolated as described in “Study design” and resuspended in Ca++-supplemented or Ca++-free solution at a concentration of 2 × 106/mL. The Ca++-free solution also contained 500 μM EGTA. ATP and ionomycin (iono) were 1 mM and 1 μM, respectively.](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/99/2/10.1182_blood.v99.2.706/6/h80221988001.jpeg?Expires=1724224352&Signature=qDo6EbIpb3o3uI1nUVErTlA9NctOV-8pF6gP3U9IYlmVkTfzigwSl~erwgnguzbwNv-yz6b~RuOPQF0VAQJU70u7cVUOKlWsmv1SNGSTHtS7~RD5NMFBvWe5s-7wFnSEcEmm72pGQlfXW3FsEJjyA0QO~umKbJwv9p-wTI7WbfjggD8vZl8CZL0K2WkJBLQ9qFV4mEuvDjS0oi0Lhy66bVxp8dTfgYC7iMajP2FT3sBCon70PoFX3HW5OXnWoM86xfrq0QJzTs1Jf3DjCG8XOZry7RWxYNIOz4aIZsBGnW8eRDrOKMsqiANN2RWir3NJzQ55jpUUrD5vW4TBm~Xr2g__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
ATP-triggered lymphocyte [Ca++] increase.
ATP triggers a higher [Ca++]iincrease in lymphocytes from evolutive (A) compared with indolent (B) B-CLL. Lymphocytes were isolated as described in “Study design” and resuspended in Ca++-supplemented or Ca++-free solution at a concentration of 2 × 106/mL. The Ca++-free solution also contained 500 μM EGTA. ATP and ionomycin (iono) were 1 mM and 1 μM, respectively.
