Kinetics of hematopoietic recovery in allogeneic full-term fetal blood recipients.

Lethally irradiated (8.5Gy) BALB/c mice were infused with full-term fetal blood from a 20-day-old C57BL/6 fetus. Peripheral blood was obtained using ethylenediaminetetracetic acid (EDTA) tubes every other week after transplantation. Data represent mean ± SD of 2 to 5 mice per timepoint. This is an experiment representative of 3 experiments. The dashed horizontal lines represent the lower and upper limits of normal. The values of blood counts in the mice receiving lethal radiation only on day +14 were as follows: WBC: 90/μL ± 38/μL blood; hematocrit: 14.5% ± 5.9%; platelet: 35.6/μL ± 20.7/μL blood. (A) White blood cells (WBC). (B) Hematocrit. (C) Platelet.