TCRBV spectratypic profiles from donor 04 for BV1 and BV13.

Profiles are for (A) preculture, (B) postculture CD8⁺selected, and (C) postculture HCMV pp65–specific HLA-A*0201 tetrameric complex–selected cells. Examples are shown of populations that were expanded after the culture that were selected based on tetramer-guided sorting (BV13—the larger of the 2 major size classes in panel B) along with those that were not selected (BV1 and BV13). In addition, the size class selected in panel C for BV1 showed no correspondingly expanded size class peak in the CD8⁺ selected population.