TCRBV spectratypic profiles from donor 02 at 2 and 3 weeks of culture.

BV6.1 profiles are shown for (A) preculture, (B) postculture unselected, (C) postculture CD8⁺ selected, and (D) postculture HCMV pp65–specific HLA-A*0201 tetrameric complex–selected cells. The tetramer-selected population showed a highly restricted repertoire. The major size class remained the same and became more apparent in the unselected population after 3 weeks of culture.