Fig. 6.
Fig. 6. CD19-mediated Akt activation is not affected by mutation of 2 YxxM motifs (Tyr482Phe, Tyr513Phe) in CD19. / DT40 cells expressing mouse wild-type CD19 or Y2FCD19 mutant (Tyr482, Tyr513 changed to Phe482, Phe513) were stimulated and subsequently subjected to the following analyses. (A) CD19-induced Akt activation. (B) Tyrosine phosphorylation of CD19.

CD19-mediated Akt activation is not affected by mutation of 2 YxxM motifs (Tyr482Phe, Tyr513Phe) in CD19.

DT40 cells expressing mouse wild-type CD19 or Y2FCD19 mutant (Tyr482, Tyr513 changed to Phe482, Phe513) were stimulated and subsequently subjected to the following analyses. (A) CD19-induced Akt activation. (B) Tyrosine phosphorylation of CD19.

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