Fig. 5.
Fig. 5. Effect of TFPI on antifibrinolytic and procoagulant potential of rFVIIa. / (A) Clys½-VIIa values of the 17 plasma samples as shown in Figure 2A (no additions), and Clys½-VIIa values of the same samples in the presence of 100 ng/mL rFL-TFPI (+ TFPI), or an inhibitory antibody against TFPI (+ α-TFPI). (B) Cclot½-VIIa values of the 17 plasma samples as shown in Figure 2B (no additions), and Cclot½-VIIa values of the same samples in the presence of 100 ng/mL rFL-TFPI (+ TFPI), or an inhibitory antibody against TFPI (+ α-TFPI).

Effect of TFPI on antifibrinolytic and procoagulant potential of rFVIIa.

(A) Clys½-VIIa values of the 17 plasma samples as shown in Figure 2A (no additions), and Clys½-VIIa values of the same samples in the presence of 100 ng/mL rFL-TFPI (+ TFPI), or an inhibitory antibody against TFPI (+ α-TFPI). (B) Cclot½-VIIa values of the 17 plasma samples as shown in Figure 2B (no additions), and Cclot½-VIIa values of the same samples in the presence of 100 ng/mL rFL-TFPI (+ TFPI), or an inhibitory antibody against TFPI (+ α-TFPI).

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