Levels of SDF-1 are reduced in BM of FucS-treated animals.

(A) SDF-1α levels in BM (circles and dashed lines) and PB (squares and solid lines) taken from the same BDF1 mice shown in Figure1C. Values at 0.5 and 1.5 hours compared with untreated controls (n = 5 per group) were statistically significant by the Studentt test for BM (P < .0001) and PB (P < .000 001) and at 3 hours for PB (n = 5;P < .000 001) but not for BM (n = 3). (B) SDF-1α levels in BM of BDF1 or B6/129 mice untreated (open bars) or 3 hours after the last of 3 intravenous injections of 100 mg/kg/d (closed bars). Values of treated compared with untreated controls were statistically significant by the Student t test (*P < .001, **P < .000 001, all groups n = 5).