Fig. 5.
Fig. 5. Levels of apoptosis are elevated incux/CDPΔHD/ΔHD thymuses and bone marrow B cells. / TUNEL apoptosis assay on sections from wild-type andcux/CDPΔHD/ΔHD thymuses demonstrates enhanced apoptosis in cux/CDPΔHD/ΔHDthymuses. The cux/CDPΔHD/ΔHD thymuses were incubated without (A) or with (C) TdT, and (B) wild-type thymus with TdT. Histograms of B-lineage cells in a B220+ gate from control (D) and cux/CDPΔHD/ΔHD (E) bone marrow stained with annexin V are shown. The percentages of annexin V+ cells within the B220+ gate from a second pair of mice were control, 20.9% andcux/CDPΔHD/ΔHD, 39.4%.

Levels of apoptosis are elevated incux/CDPΔHD/ΔHD thymuses and bone marrow B cells.

TUNEL apoptosis assay on sections from wild-type andcux/CDPΔHD/ΔHD thymuses demonstrates enhanced apoptosis in cux/CDPΔHD/ΔHDthymuses. The cux/CDPΔHD/ΔHD thymuses were incubated without (A) or with (C) TdT, and (B) wild-type thymus with TdT. Histograms of B-lineage cells in a B220+ gate from control (D) and cux/CDPΔHD/ΔHD (E) bone marrow stained with annexin V are shown. The percentages of annexin V+ cells within the B220+ gate from a second pair of mice were control, 20.9% andcux/CDPΔHD/ΔHD, 39.4%.

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