Reduction in Bcr-Abl protein expression upon withdrawal of STI571 from LAMA84-r cultures.

Total cellular protein was harvested from parallel cultures growing in the presence or absence of 1 μM STI571 for the periods indicated and subjected to Western analysis with anti-Abl (Bcr-Abl band shown) and antiactin antibodies. Densitometric analysis of the Bcr-Abl signal relative to that of actin is presented for each lane.