TCR Vβ repertoire analysis of PBMCs from IM donors during acute infection and recovery.

Depicted are the Vβ values of the known 1 to 25 families with significant expansions. Significance was based on at least a 2-fold magnitude change and P < .05 against a control background (see “Materials and methods”). Profiles are displayed of fluorescence intensity (x-axis, arbitrary units) as a function of CDR3 size (y-axis, amino acids). CDR3 peaks are spaced 3 nucleotides apart. ND indicates not done; NP, not present.