Fig. 4.
PrPC colocalizes with the MHC class II compartment in monocyte-derived DCs.
Adherent immature monocyte-derived DCs were allowed to ingest FITC-dextran for 15 minutes to reveal endocytic vesicles (A), stained for talin to reveal adhesion plaques (B), or stained for MHC class II molecules to reveal the MHC class II compartment (C). PrPCis shown in red in each instance. Colocalization of green-red signal gives yellow fluorescence.
