Fig. 3.
Fig. 3. The effect of Fc-OPG on lytic bone lesions induced by 5T2MM cells. / (A) Radiograph of the tibia and femur from a control, uninjected animal. (B) Radiograph of the tibia and femur of an animal injected with 5T2MM cells and vehicle, showing the presence of lytic lesions (arrows). (C) Radiograph of the tibia and femur of an animal injected with 5T2MM cells and OPG. (D) Number of osteolytic bone lesions in the femora of control animals, animals injected with 5T2MM cells and vehicle, and animals injected with 5T2MM cells and OPG. (E) Number of osteolytic bone lesions in the tibiae of control animals, animals injected with 5T2MM cells and vehicle, and animals injected with 5T2MM cells and OPG.

The effect of Fc-OPG on lytic bone lesions induced by 5T2MM cells.

(A) Radiograph of the tibia and femur from a control, uninjected animal. (B) Radiograph of the tibia and femur of an animal injected with 5T2MM cells and vehicle, showing the presence of lytic lesions (arrows). (C) Radiograph of the tibia and femur of an animal injected with 5T2MM cells and OPG. (D) Number of osteolytic bone lesions in the femora of control animals, animals injected with 5T2MM cells and vehicle, and animals injected with 5T2MM cells and OPG. (E) Number of osteolytic bone lesions in the tibiae of control animals, animals injected with 5T2MM cells and vehicle, and animals injected with 5T2MM cells and OPG.

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