Truncated haptoglobin inhibits the oxidation of linolenic acid by hemoglobin.

Recombinant haptoglobin was produced as described in “Materials and methods.” (A) Lack of inhibition of oxidation of linolenic acid by a 40–amino acid construct RHp3 (derived from RHp2). (B) Concentration-dependent inhibition of oxidation of linolenic acid by an 81–amino acid construct derived from the haptoglobin β-chain (RHp2).