Fig. 8.
![Fig. 8. In vivo OPG/OPGL imbalance in MM patients' BM sections compared with healthy donors. / OPGL immunostaining of (A) infiltrating myeloma cells in the BM of MM patients (original magnification × 100; 12 μm); (B,C) stromal cells in a biopsy specimen from MM patient with osteolytic lesions (original magnification × 20; 50 μm [B] and × 40; 25 μm [C]); and (D) BM biopsy of a healthy subject (original magnification × 20; 50 μm). (E,F) OPG immunostaining in a representative trabecula of an MM patient with osteolytic lesions (E) and a healthy subject (F) (original magnification × 30; 35 μm).](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/98/13/10.1182_blood.v98.13.3527/6/h82411867008.jpeg?Expires=1724241929&Signature=EXccSXYHQhvsGQ5eu2YBT4zPXGuE3uFkthnqg9JadZRIBcjUgsv0BhoUGocasTRAXe1RQ2S2W43wWJFzKmsUukWFUdUw2ctbLjHo3plj1dFnApQzynUE8avEzb4l9RcXdNmF8aiZfVUVwHBaJCVO17O8uC-9xTQM0rplD2PD7MkYpIk9lTlbK3UHQivrnrglpCWnFJt5CiQtwmT6eQ1YBCkY6oaPVDbaORksOYZeNggcRNep4FjWXamzI~K-6TBzpiyzGEVf5k2adY6k4VxXPGrgx4f9BJVd7jHycuLcH3FvfTRrqRW1BOVCw-5cVqRQNqGkYgTtiRxpmMAAdOIGpw__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
In vivo OPG/OPGL imbalance in MM patients' BM sections compared with healthy donors.
OPGL immunostaining of (A) infiltrating myeloma cells in the BM of MM patients (original magnification × 100; 12 μm); (B,C) stromal cells in a biopsy specimen from MM patient with osteolytic lesions (original magnification × 20; 50 μm [B] and × 40; 25 μm [C]); and (D) BM biopsy of a healthy subject (original magnification × 20; 50 μm). (E,F) OPG immunostaining in a representative trabecula of an MM patient with osteolytic lesions (E) and a healthy subject (F) (original magnification × 30; 35 μm).
