Fig. 7.
Fig. 7. Lack of protection from CDDO-Me–induced apoptosis conferred by Bcl-2 in U937 cells. / U937 cells transduced with Bcl-2 (U937/Bcl-2) and their empty-vector counterparts (pCEP) were treated with the indicated concentrations of CDDO-Me for 24 hours. Growth inhibition was determined by cell count; changes in the mitochondrial membrane potential were measured by CMXRos staining (Δψm). Western blot demonstrates elevated Bcl-2 levels in the U937/Bcl-2 cells.

Lack of protection from CDDO-Me–induced apoptosis conferred by Bcl-2 in U937 cells.

U937 cells transduced with Bcl-2 (U937/Bcl-2) and their empty-vector counterparts (pCEP) were treated with the indicated concentrations of CDDO-Me for 24 hours. Growth inhibition was determined by cell count; changes in the mitochondrial membrane potential were measured by CMXRos staining (Δψm). Western blot demonstrates elevated Bcl-2 levels in the U937/Bcl-2 cells.

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