Fig. 2.
CDDO-Me induction of apoptosis in primary AML samples.
AML blasts from AML samples 1 to 4 were grown in the presence of 0.1 and 0.5 μM CDDO-Me (A), and AML samples 5 to 11 at 1 or 5 μM for 48 hours (B). Apoptosis was measured by subG1-DNA flow cytometry (AO, acridine orange).